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Common Uses

SEASONALE® is the FDA-approved extended-cycle birth control pill for the prevention of pregnancy that reduces your monthly periods to just 4 times a year.

Before Using

PLEASE CONSULT WITH YOUR PHYSICIAN OR OTHER QUALIFIED HEALTHCARE PROFESSIONAL BEFORE USING ANY PRODUCT DISCUSSED HERE OR WITHIN ANY OF OUR OTHER WEB SITES. Promptly see a qualified healthcare professional if you have, or suspect that you have, a medical condition. This site may contain information related to various health, medical and fitness conditions and their treatment. However, we do not offer individualized medical diagnosis or patient-specific treatment advice. You should not use the information contained herein for diagnosing or treating a medical condition or disease. You should always consult a qualified healthcare professional before initiating use of any medicine or other treatment. Only a qualified healthcare professional can determine if a product described here, or within any of our other Web sites, would be appropriate for you to use. Your qualified healthcare professional is in the best position to discuss with you the risks and benefits of any treatment, including prescription drugs, specific to your own medical condition.


Take 1 pink tablet daily for 84 consecutive days. Follow with 7 days of white inactive tablets. Begin taking SEASONALE® on the first Sunday after the onset of menstruation. If menstruation begins on a Sunday, the first pink tablet is taken that day. Withdrawal bleeding should occur during the 7 days following discontinuation of pink active tablets.

Possible Side Effects

Serious as well as minor side effects have been reported with the use of hormonal contraceptives. Serious risks include blood clots, stroke, and heart attack. Cigarette smoking increases the risk of serious cardiovascular side effects, especially in women over 35 years. Oral contraceptives do not protect against HIV infection (AIDS) and other sexually transmitted diseases.

Possible Food & Drug Interactions

Changes in contraceptive effectiveness associated with co-administration of other products:
  1. Anti-infective agents and anticonvulsants
    Contraceptive effectiveness may be reduced when hormonal contraceptives are coadministered with antibiotics, anticonvulsants, and other drugs that increase the metabolism of contraceptive steroids. This could result in unintended pregnancy or breakthrough bleeding. Examples include rifampin, barbiturates, phenylbutazone, phenytoin, carbamazepine, felbamate, oxcarbazepine, topiramate, and griseofulvin. Several cases of contraceptive failure and breakthrough bleeding have been reported in the literature with concomitant administration of antibiotics such as ampicillin and tetracyclines. However, clinical pharmacology studies investigating drug interaction between combined oral contraceptives and these antibiotics have reported inconsistent results.

  2. Anti-HIV protease inhibitors
    Several of the anti-HIV protease inhibitors have been studied with co-administration of oral combination hormonal contraceptives; significant changes (increase and decrease) in the plasma levels of the estrogen and progestin have been noted in some cases. The safety and efficacy of combination oral contraceptive products may be affected with co-administration of anti-HIV protease inhibitors. Healthcare providers should refer to the label of the individual anti-HIV protease inhibitors for further drug-drug interaction information.

  3. Herbal products
    Herbal products containing St. John s Wort (hypericum perforatum) may induce hepatic enzymes (cytochrome P450) and p-glycoprotein transporter and may reduce the effectiveness of contraceptive steroids. This may also result in breakthrough bleeding.

Important Fact

If you MISS 1 pink active pill:
1. Take it as soon as you remember. Take the next pill at your regular time. This means you may take 2 pills in 1 day.
2. You do not need to use a back-up birth control method if you have sex.

If you MISS 2 pink active pills in a row:
1. Take 2 pills on the day you remember, and 2 pills the next day.
2. Then take 1 pill a day until you finish the pack.
3. You COULD BECOME PREGNANT if you have sex in the 7 days after you restart your pills. You MUST use another birth control method (such as condoms or spermicide) as a back-up on the 7 days after you restart your pills.

If you MISS 3 OR MORE pink active pills in a row:
1. Do not remove the missed pills from the pack as they will not be taken. Keep taking 1 pill every day as indicated on the pack until you have completed all of the remaining pills in the pack. For example: If you resume taking the pill on Thursday, take the pill under Thursday and do not take the missed pills. You may experience bleeding during the week following the missed pills.
2. You COULD BECOME PREGNANT if you have sex during the days of missed pills or during the first 7 days after restarting your pills.
3. You must use a non-hormonal birth control method (such as condoms or spermicide) as a back-up when you miss pills and for the first 7 days after you restart your pills. If you miss your period when you are taking the white pills, call your healthcare provider because you may be pregnant.

If you MISS ANY of the 7 white inactive pills.
1. Throw away the missed pills.
2. Keep taking the scheduled pills until the pack is finished.
3. You do not need a back-up method of birth control.

1. Use a BACK-UP METHOD anytime you have sex.
2. KEEP TAKING ONE PILL EACH DAY until you contact your healthcare provider.

If you take too much

If overdose is suspected, contact your local poison control center or emergency room immediately. DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out.

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